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frederica theodoulou


Prof. Frederica Theodoulou

Science Director

Plant Sciences for the Bioeconomy

Rothamsted Research, Harpenden, AL5 2JQ
+44 (0) 1582 938 264
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Freddie is Director of the Plant Sciences for the Bioeconomy Strategic Area and leads the Green Engineering Institute Strategic Programme. Her research focuses on diverse aspects of plant proteostasis, from deciphering fundamental mechanisms governing the synthesis and degradation of proteins, to the ultimate application of this knowledge for crop improvement. To address these challenges, our diverse team uses a range of techniques including biochemistry, molecular biology, genetics, statistical genetics, and multi-omic analysis. Current interests include:

•    Understanding the genetic architecture of protein abundance in plants

•    Targeted protein degradation mechanisms, in particular the N-degron pathways

•    Proteostatic and other mechanisms involved in oxygen sensing and flood tolerance

•    Tools to study protein lifetime

•    The impact of transgenesis on the proteome

Strategic Programme

  • Green Engineering

Science Projects

  • What determines protein abundance in plants? This BBSRC-funded, multi-partner strategic Longer Larger grant seeks to determine the (epi)genetic drivers of protein abundance in Arabidopsis

PhD Projects

  • Understanding the mechanisms of hypoxia tolerance in rice


  • 1992 - DPhil, Department of Plant Sciences, University of Oxford, UK
  • 1989 - BA (Hons), first class, Botany, University of Oxford, UK

Measures of Esteem

  • 2015 - Honorary Professor (Plant Biochemistry), Department of Animal and Plant Sciences, University of Sheffield