NMR and Bio-Analytical Chemistry Capabilities

Ascend 700MHz 

• Solid state, equipped with the UK’s first CPMAS cryo-biosolids probe, available nuclei 1H, 2H, 13C, 15N
• Analysis of biomolecules and small molecules in solid materials 

Bruker 600 MHz NMR with Samplejet autosampler

• 600 MHz (solution state, equipped with 3-channel TCI-helium cryoprobe, available nuclei 1H, 2H, 13C, 15N, 19F).
• Analysis of biomolecules and small molecules in solution.
• High throughput, fully automated analysis 

Gas Chromatography - MS

Agilent 8890B GC-MSD with NIST library (EI Source) 

• Separation and identification of volatile and semi-volatile organic compounds in complex matrices

Agilent 8890B GC Triple Quadrupole with NIST library (EI Source) 

• Targeted, high-sensitivity quantification of volatile and semi-volatile organic compounds in complex matrices

Agilent 8890B GC QTOF with NIST library (EI source) 

• High-resolution non-target analysis and identification of volatile and semi-volatile organic compounds in complex matrices

Liquid Chromatography - MS

Waters Synapt G2Si QTOF with Acquity UPLC I-class system (ESI source) 

• High-resolution and ion mobility-enabled analysis of polar and non-volatile small molecules and biomolecules for targeted and non-target screening in complex solid and liquid matrices

SFC-HPLC-MS

Shimadzu Nexera UC Prep SFC/HPLC hybrid system, equipped with a single quad MS (ESI/APCI source) and automated fraction collection

• Separation, purification, and analysis of low- to medium-polarity small molecules using supercritical fluid and liquid chromatography with targeted detection in complex matrices.
• Mass guided automated fractionation of complex mixtures (e.g. natural products, synthetic reaction mixtures, environmental samples)