RNAI AS A PEST MANAGEMENT TOOL IN APHIDS
AREA OF SCIENCE:
Sunday, December 1, 2019 - 00:00
Biointeractions and Crop Protection
University of Nottingham
Project funded by AHDB Cereals & Oilseeds
An exciting opportunity for a 3-year AHDB-funded PhD on ‘targeted gene silencing’ to control aphid infestations in UK cereals and oilseeds. This studentship will investigate how best to optimize dsRNAi design and delivery for effective gene knockdown in aphids. There are currently several challenges to be addressed for such an RNAi approach to be effective, including the probability of dsRNA degradation by proteases present in the aphid gut and saliva, efficient uptake and translocation of the dsRNA in crop plants that the aphids feed upon, development of effective topical delivery methods, such as nano-particle conjugation, and achieving a sufficient dose of bio-aphicide to realize good control. To translate RNAi to field applicability, RNAi silencing elicitors will need to be combined with biotic or abiotic systems that mediate both protection and uptake of the eliciting RNAi trigger.
This studentship will be based at Rothamsted Research, Harpenden.
Applicants should hold a minimum of a UK Honours Degree at 2:1 level or equivalent in relevant subject areas.
The successful student will be supported by the tax-free stipend of £15,009 for 3 years. In addition, for eligible students, the award will cover fees for EU/UK nationals and a Research and Training Grant to fund their research, conference attendance and networking.
To apply for this project, please complete our Rothamsted PhD Application Form
All applications should include a fully completed application form, CV, a transcript of module marks and two references.
The reference form which will need to be completed by your referees can be found on the downloads section of this advert. These references should be sent directly from the referees to Donna Fellowes; firstname.lastname@example.org as soon as possible after applying.
PLEASE ENSURE THAT YOU CONTACT YOUR REFEREES AND LET THEM KNOW THAT WE NEED THEIR REFERENCES AS SOON AS POSSIBLE.