Insect Molecular Biologist

Head of Biointeractions and Crop Protection

Biointeractions and Crop Protection


Lin is an insect molecular biologist and Head of Biointeractions and Crop Protection at Rothamsted Research. Her personal research interests are focused on understanding insecticide mode of action and resistance at the biochemical/molecular level. Her research team uses the latest genomic techniques to understand resistance and insecticide selectivity, and seeks to apply this understanding to better use of pesticides through links with partners in the agronomy, farming and agro-chemical sectors. As head of department, Lin has also developed a wide knowledge of alternative pest control strategies, especially the use of chemical ecology approaches and including the use of GM technologies. The overall aim of Lin's work is to deliver effective and sustainable crop protection strategies that minimise the effects on non-targets and the environment. Lin has been, and continues to be, an active participant in the debate on whether pesticides are needed and how they may affect bee populations. This has involved speaking to fellow scientists, farmers/growers, bee keepers, policy makers and the general public. Going forward, Lin will seek to oversee and co-ordinate her department’s work, and sees her role as being to bring together multi-disciplinary groups of researchers to deliver excellent science into the crop protection arena.




    +44 (0) 1582 938 355


      Rothamsted Research, Harpenden, AL5 2JQ


        • 2007
          Davies, T. G. E.,Field, L. M.,Usherwood, P. N. R.,Williamson, M. S.

          DDT, pyrethrins, pyrethroids and insect sodium channels

          IUBMB Life 59 : pp.151-162
          doi: 10.1080/15216540701352042

        • 2007
          Bingham, G.,Gunning, R. V.,Gorman, K. J.,Field, L. M.,Moores, G. D.

          Temporal synergism by microencapsulation of piperonyl butoxide and alpha-cypermethrin overcomes insecticide resistance in crop pests

          Pest Management Science 63 : pp.276-281
          doi: 10.1002/ps.1336

        • 2006
          Gunning, R. V.,Nicholson, I. C.,Kemp, F. C.,Borzatta, V.,Cottage, E. L. A.,Field, L. M.,Moores, G. D.

          Piperonyl butoxide, restores the efficacy of Bacillus thuringiensis toxin in transgenic cotton against resistant Helicoverpa armigera

          Biopesticides International 2 : pp.129-136

        • 2006
          Zhou, J-J.,Kan, Y.,Antoniw, J. F.,Pickett, J. A.,Field, L. M.

          Genome and EST analyses and expression of a gene family with putative functions in insect chemoreception

          Chemical Senses 31 : pp.453-465
          doi: 10.1093/chemse/bjj050

        • 2006
          Beale, M. H.,Birkett, M. A.,Bruce, T. J. A.,Chamberlain, K.,Field, L. M.,Huttly, A. K.,Martin, J. L.,Parker, R.,Phillips, A. L.,Pickett, J. A.,Prosser, I. M.,Shewry, P. R.,Smart, L. E.,Wadhams, L. J.,Woodcock, C. M.,Zhang, Y.

          Aphid alarm pheromone produced by transgenic plants affects aphid and parasitoid behavior

          Proceedings of the National Academy of Sciences of the United States of America 103 : pp.10509-10513
          doi: 10.1073/pnas.0603998103 Open Access

        • 2006
          Prosser, I. M.,Adams, R. J.,Beale, M. H.,Hawkins, N. D.,Phillips, A. L.,Pickett, J. A.,Field, L. M.

          Cloning and functional characterisation of a cis -muuroladiene synthase from black peppermint (Mentha x piperita) and direct evidence for a chemotype unable to synthesise farnesene

          Phytochemistry 67 : pp.1564-1571
          doi: 10.1016/j.phytochem.2005.06.012

        • 2006
          O'Reilly, A. O.,Khambay, B. P. S.,Williamson, M. S.,Field, L. M.,Wallace, B. A.,Davies, T. G. E.

          Modelling insecticide-binding sites in the voltage-gated sodium channel

          Biochemical Journal 396 : pp.255-263
          doi: 10.1042/BJ20051925

        • 2006
          Bass, C. G.,Lansdell, S. J.,Millar, N. S.,Schroeder, I.,Turberg, A.,Field, L. M.,Williamson, M. S.

          Molecular characterisation of nicotinic acetylcholine receptor subunits from the cat flea, Ctenocephalides felis (Siphonaptera: Pulicidae)

          Insect Biochemistry and Molecular Biology 36 : pp.86-96
          doi: 10.1016/j.ibmb.2005.11.003

        • 2005
          Jacobs, S. P.,Liggins, A. P.,Zhou, J-J.,Pickett, J. A.,Jin, X.,Field, L. M.

          OS-D- like genes and their expression in aphids (Hemiptera: Aphididae)

          Insect Molecular Biology 14 : pp.423-432

        • 2005
          Li, Z-X.,Pickett, J. A.,Field, L. M.,Zhou, J-J.

          Identification and expression of odorant-binding proteins of the malaria-carrying mosquitoes Anopheles gambiae and Anopheles arabiensis

          Archives of Insect Biochemistry and Physiology 58 : pp.175-189

        • 2004
          Li, Z. X.,Zhou, J-J.,Shen, Z. R.,Field, L. M.

          Identification and expression profiling of putative odorant-binding proteins in the malaria mosquitoes, Anopheles gambiae and A. arabiensis

          Science in China, Series C - Life Sciences 47 : pp.567-576

        • 2004
          Bass, C. G.,Schroeder, I.,Turberg, A.,Field, L. M.,Williamson, M. S.

          Identification of mutations associated with pyrethroid resistance in the para -type sodium channel of the cat flea, Ctenocephalides felis

          Insect Biochemistry and Molecular Biology 34 : pp.1305-1313

        • 2004
          Andrews, M. C.,Callaghan, A.,Field, L. M.,Wiliamson, M. S.,Moores, G. D.

          Identification of mutations conferring insecticide-insensitive AChE in the cotton-melon aphid, Aphis gossypii Glover

          Insect Molecular Biology 13 : pp.555-561
          doi: 10.1111/j.0962-1075.2004.00517.x

        • 2004
          Bass, C. G.,Schroeder, I.,Turberg, A.,Field, L. M.,Williamson, M. S.

          Identification of the RD1 mutation in laboratory and field strains of the cat flea, Ctenocephalides felis (Siphonaptera: Pulicidae)

          Pest Management Science 60 : pp.1157-1162

        • 2004
          Field, L. M.,Lyko, F.,Mandrioli, M.,Prantera, G.

          DNA methylation in insects

          Insect Molecular Biology 13(2) : pp.109-115
          doi: 10.1111/j.0962-1075.2004.00470.x

        • 2004
          Zhou, J-J.,Huang, W.,Zhang, G-A.,Pickett, J. A.,Field, L. M.

          "Plus-C" odorant-binding protein genes in two Drosophila species and the malaria mosquito Anopheles gambiae

          Gene 327(1) : pp.117-129
          doi: 10.1016/j.gene.2003.11.007

        • 2004
          Zhou, J-J.,Zhang, G-A.,Huang, W.,Birkett, M. A.,Field, L. M.,Pickett, J. A.,Pelosi, P.

          Revisiting the odorant-binding protein LUSH of Drosophila melanogaster : evidence for odour recognition and discrimination

          FEBS Letters 558 : pp.23-26

        • 2003
          Javed, N.,Viner, R.,Williamson, M. S.,Field, L. M.,Devonshire, A. L.,Moores, G. D.

          Characterization of acetylcholinesterases, and their genes, from the hemipteran species Myzus persicae (Sulzer), Aphis gossypii (Glover), Bemisia tabaci (Gennadius) and Trialeurodes vaporariorum (Westwood)

          Insect Molecular Biology 12 : pp.613-620

        • 2003
          Moss, S. R.,Cocker, K. M.,Brown, A. C.,Hall, L.,Field, L. M.

          Characterisation of target-site resistance to ACCase-inhibiting herbicides in the weed Alopecurus myosuroides (black-grass)

          Pest Management Science 59 : pp.190-201

        • 2003
          Field, L. M.,Blackman, R. L.

          Insecticide resistance in the aphid Myzus persicae (Sulzer): chromosome location and epigenetic effects on esterase gene expression in clonal linkages

          Biological Journal of the Linnean Society 79 : pp.107-113


        Strategic programme

        • Smart Crop Protection (SCP)

        PhD project

        • Investigation and characterisation of diamide insecticide resistance conferred by target-site mutations in the ryanodine receptor of lepidopteran pests with special reference to diamondback moth, Plutella xylostella
        • Quantifying the impacts of the neonicotinoid ban on oilseed rape pest control, pollination and productivity
        • New opportunities to investigate insecticide and acaricide ion channel targets through their differential interactions with novel chemical agonists
        • Innovating insect production to counter malnutrition and support aquaculture in Africa
        • Unravelling interactions between cereal aphids and ancestral wheat lines to elucidate mechanisms of aphid resistance.


        • 1989 - PhD (CNAA), The Molecular Genetic Basis of Insecticide Resistance in the Peach-Potato Aphid, Myzus persicae
        • 1986 - BA (Hons) First Class, Open University


        • 2015 - Expert Reviewer for Intergovernmental Platform on Biodiversity and Ecosystem Services (IPBES) Deliverable 3(a) report
        • present - Member Science about Science Plant Science Panel
        • 2013 - Member Government Office Food Research Partnership sub-group New Innovative Approaches to Crop Protection
        • 2013-14 - Member Defra Advisory Committee Pollinators
        • 2012-2015 - Member Agreen Skill EU Committee
        • 2010-2013 - Member of Royal Society Dorothy Hodgkin Fellowship Panel
        • 2011-2014 - Member of BBSRC Research Committee B
        • Present - Honorary Professor University of Nottingham
        • Present - Fellow of the Royal Society of Biology
        • Present - Fellow of the Royal Entomological Society
        • Present - Editorial Officer, Royal Entomological Society
        • Present - Member of Editorial Board for Insect Molecular Biology