Rothamsted Research offers a cereal transformation service to generate transgenic wheat plants for research purposes for both internal projects and external contracts.
The Cereal Transformation Group has a long history of wheat transformation research and has developed optimised protocols for both particle bombardment and Agrobacterium-mediated transformation, successfully transforming over 40 different wheat and wheat-related varieties. Both internal projects and external contracts can be supported with costs being dependent on the service required.
Advice is available on all aspects of transformation from the design stages such as suggesting promoters to drive transgene expression or providing appropriate cloning constructs for either overexpression of genes or their down-regulation by RNAi, to assistance with crossing transgenic plants or taking transgenic lines to field trial.
A more recent addition to transformation technology is genome editing which offers the possibility to generate highly targeted mutations in the host genome. Some success has already been achieved in modifying specific target genes and the intention is to add this to the range of services offered.