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BBSRC Institute Development Fellowship




Surface coat variation in C. elegans
Plant Pathology and Microbiology, Rothamsted Research, Harpenden, Herts., AL5 2JQ, UK.
Telephone: +44 (0)1582 763133 x2220. Fax: +44 (0)1582 760981
This project is in collaboration with Prof Jonathan Hodgkin, Department of Biochemistry, University of Oxford, and aims at identifying and characterising genes that lead to changes in the cuticle of Caenorhabditis elegans that affect sensitively to the bacterium Microbacterium nematophilum and seeing if similar genes are present in plant parasitic nematodes that relate to the sensitivity of plant parasitic nematodes to Pasteuria penetrans. Understanding the genetics of cuticle variation in relationship to Pasteuria pathogenesis will help in the deployment of strains of Pasteuria that can suppress plant parasitic nematode pests and act as a biological control agent as an alternative to using chemical pesticides.

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Recent presentations & posters

Davies, K.G., Gravato-Nobre, M. and Hodgkin, J. (2009) Knock-down of mucin-like genes using RNAi changed lectin staining in adult hermaphrodites of Caenorhabditis elegans. 17th International C. elegans Meeting, University of California, Los Angeles