
RFLP
Restriction Fragment Length Polymorphism: used to describe the variation in the length of the DNA fragments obtained
when the same gene from different individuals or species is cut with the same restriction enzyme.
RFLP is used to diagnose some genetic diseases, like sickle-cell anemia, or to do phylogenetic analysis.
View Dr Chromo's lecture on 'Digestion of DNA'.
Related Links
This is a search for rflp in our database
- DistinctiEnz: DistinctiEnz is a Bioperl tool used to perform a virtual RFLP and more
- Paper on FreeTree - tree computation program: It was originally intended for the analysis of results of DNA fingerprinting methods (RFLP, RAPD, AP-PCR) or other methods which provide binary character data (presence/absence of the characters). For such data the program computes the distance matrix, constructs the phylogenetic or phenetic tree and computes bootstrapping or jackknifing values for internal branches of the tree.