Animated Dictionnary Definition

Protein

Major class of biological compounds. Proteins are made of amino acids and are varied in shape, size and role.

View an example of protein in Rasmol

View Dr Chromo's lecture on 'Proteins'.

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This is a search for protein in our database

2Can ebi tutorials: Learn how to use the tools at the EBI to find out more about your nucleotide or protein sequences. You will be guided through a series of exercises using sample fragments of sequence. To gain more information about these sequences, you will use a variety of tools to compare the sequences to databases and analyse them.
A Gene Map of the Human Genome: The Human Genome Project is expected to produce a sequence of DNA representing the functional blueprint and evolutionary history of the human species. However, only about 3% of this sequence is thought to specify the portions of our 50,000 to 100,000 genes that encode proteins. '
BALIBASE - A benchmark alignment database: BAliBASE 2.0 includes three new alignment references sets (references 6-8) containing 26 protein families with 12 distinct repeat types, 9 transmembrane families and 5 families with inverted domains, representing more than 1100 sequences. As in references 1-5, core blocks are defined that only include the repeated/inverted domains and the transmembrane helices.
Bioinformatics of Membrane Protein Structure: University of Luton Membrane Proteins Group.
BioMolecular Engineering Research Center: The BMERC is using and creating tools and methods for the study of computational biology. The center is working on secondary protein structure prediction, providing reliable profiles, and developing new ways to study molecular biology through Bioinformatics. Our work has led to the formulation and testing of major hypotheses in the areas of molecular evolution, gene regulation, developmental genetics, and protein structure-function relationships.
BLAST: BLAST (Basic Local Alignment Search Tool) is a set of similarity search programs designed to explore all of the available sequence databases regardless of whether the query is protein or DNA. The BLAST programs have been designed for speed, with a minimal sacrifice of sensitivity to distant sequence relationships. The scores assigned in a BLAST search have a well-defined statistical interpretation, making real matches easier to distinguish from random background hits. BLAST uses a heuristic algorithm which seeks local as opposed to global alignments and is therefore able to detect relationships among sequences which share only isolated regions of similarity (Altschul et al., 1990).
CATH: Protein Structure Classification: CATH is a novel hierarchical classification of protein domain structures, which clusters proteins at four major levels, class(C), architecture(A), topology(T) and homologous superfamily (H). Class, derived from secondary structure content, is assigned for more than 90% of protein structures automatically. Architecture, which describes the gross orientation of secondary structures, independent of connectivities, is currently assigned manually. The topology level clusters structures according to their toplogical connections and numbers of secondary structures. The homologous superfamilies cluster proteins with highly similar structures and functions. The assignments of structures to toplogy families and homologous superfamilies are made by sequence and structure comparisons.
Central dogma of molecular biology: The dogma is a framework for understanding the transfer of sequenceSequence In mathematics, a sequence is an ordered list of objects . Like a Set , it contains Element , and the number of terms is called the length of the sequence.... informationInformation Information as a Conveyed concept has a diversity of meanings, from everyday usage to technical settings. Generally speaking, the concept of information is closely related to notions of constraint, communication, control system, data, form, instruction, knowledge, Meaning , stimulation, pattern, perception, and knowledge representation.... between sequential information-carrying biopolymerBiopolymer Biopolymers are a class of polymers produced by living organisms.Starch, proteins and peptides,and DNA and RNA are all examples of biopolymers, in which the monomeric units, respectively, are sugars, amino acids, and nucleotides.... s, in the most common or general case, in living organismOrganism In biology, an organism is any life thing . In at least some form, all organisms are capable of response to stimulus , reproduction, growth and developmental biology, and maintenance of homeostasis as a stable whole.... s.
ChromDB: The Plant Chromatin Database: The mission of ChromDB is to bring together information on homologs of chromatin-associated proteins encoded by plant genomes, organize this information logically and in a comparative manner across species (with reference to other eukaryotes to the extent possible), and make it readily accessible to any members of the research and teaching communities who might be interested in the role played by chromatin proteins in the control of gene expression and genome organization. Our first priority is to provide (a) complete sets of genes encoding chromatin-associated proteins (CAPs) for those plant species with complete or near-complete genome sequences (currently Arabidopsis and rice, with poplar to be displayed in the future), (b) the best available splicing models and predicted protein sequences for these genes, and (c) a molecular phylogenetic context for understanding the evolutionary diversification of these protein families during plant evolution with reference to animal and fungal homologs. Our next priorities will be to identify and present CAP genes in all available EST and partial genomic sequences of other plant species, as well as to provide information regarding their biochemical, developmental, physiological, and cellular functions through a community annotation mechanism.
Cis-Peptide Bonds in Proteins: The IMB Jena Image Library of Biological Macromolecules contains visual and other information on three-dimensional biopolymer structures. It provides access to all structure entries deposited at the Protein Data Bank (PDB) or at the Nucleic Acid Database (NDB).
Clustal W: Clustal W is a general purpose multiple sequence alignment program for DNA or proteins.It produces biologically meaningful multiple sequence alignments of divergent sequences. It calculates the best match for the selected sequences, and lines them up so that the identities, similarities and differences can be seen. Evolutionary relationships can be seen via viewing Cladograms or Phylograms.
Computational Genomic Group (CGG): Computational approaches for analysis of nucleotide and protein sequences and structures as well as understanding structural and functional organization of genetic signals encoded in genome sequences.
Crystallography on the Web: This site provides information regarding Protein Crystallography and the principles of protein structure.
deCODE: what is your name in DNA: In the seconds it takes after you press the above deCODE button, I will ...
-Change the letters of your name to the closest DNA bases...
-Search every one of 168,297 protein sequences from 8826 animals, plants and microorganisms...
-And return to you, the protein that contains the closest match to... the letters of your name !!
Deep View SPDB viewer: Swiss-PdbViewer is an application that provides a user friendly interface allowing to analyse several proteins at the same time. The proteins can be superimposed in order to deduce structural alignments and compare their active sites or any other relevant parts. Amino acid mutations, H-bonds, angles and distances between atoms are easy to obtain thanks to the intuitive graphic and menu interface.
Deep View Tutorial (SPDB viewer): This tutorial provides an introduction to macromolecular modeling with Deep View, including review of many basic concepts in protein structure.
Deoxy-Ribonucleotides and Watson-Crick Basepairs: The IMB Jena Image Library of Biological Macromolecules contains visual and other information on three-dimensional biopolymer structures. It provides access to all structure entries deposited at the Protein Data Bank (PDB) or at the Nucleic Acid Database (NDB).
Design PCR Primers: tools: A list of free web applications to design PCR primers: including alignment primers, primers for RAPDS and from protein sequences. This team has done a great job at reviewing what is there.
DIP: Database of Interactive Proteins: The DIPTM database catalogs experimentally determined interactions between proteins. It combines information from a variety of sources to create a single, consistent set of protein-protein interactions.
Discovery Studio: Discovery Studio is a protein modeling program that contains tools to visualize, analyze, modify and simulate protein structures.
DNA Workshop: The activity in this section places you within the cell, involving you with the processes of DNA replication and protein synthesis.
DNA2.0 Bioinformatics toolbox: This collection of javascript bioinformatics software is a convenient, user friendly and free resource for anyone interested in generating, formatting and analyzing DNA and protein sequences. The goal here is to support your gene design efforts as much as possible so that you can focus on doing research instead of spending time on decoding cryptic software manuals.
Endoplasmic Reticulum: Structure and Function : Endoplasmic reticulum is a network of tubules, vesicles and sacs that are interconnected. They may serve specialized functions in the cell including protein synthesis, sequestration of calcium, production of steroids, storage and production of glycogen, and insertion of membrane proteins. ...
Enzymatic RNA Molecules and the Replication of Chromosome Ends: A cell must orchestrate thousands of chemical reactions in order to live, to grow, and to respond to its environment. These chemical reactions rarely happen spontaneously but are usually catalyzed by macromolecules called enzymes. It was long thought that all enzymes were proteins. More recently we and others have found that RNA can in some cases act as an enzyme.
GeneCards: GeneCards is a database of human genes, their products and their involvement in diseases. It offers concise information about the functions of all human genes that have an approved symbol, as well as selected others [gene listing]. It is especially useful for those who are searching for information about large sets of genes or proteins, e.g. for scientists working in functional genomics and proteomics.
Geneious website: Geneious combines all the leading DNA and protein sequence analysis tools into one revolutionary software solution! Its ease of use makes bioinformatics accessible to any biologist. It runs on all major operating systems and is very affordable.
Genomics Jump station: The Genomics Jump Station: The ultimate Web page for information and links on all aspects of Genomics Research. Institutes and groups involved in functional genomics, companies involved in functional genomics, publications on functional genomics, analysis of protein sequences, analysis of DNA sequences.
Homology Modeling for Beginners: Homology models are useful to get a rough idea where the alpha carbons of key residues sit the folded protein. They can guide mutagenesis experiments, or hypotheses about structure-function relationships.
HUSAR: We put the most up-to-date databases and software packages at your fingertips. Our main program package - HUSAR - offers more than 250 applications for DNA and protein analysis. In addition to the latest, complete version of the GCG package (which makes up only about 50% of our applications), you can use tools developed by us and by ranking researchers in the bioinformatics field.
Identifying mutations in genes encoding insecticide target proteins: We have played a leading role in identifying mutations in the insect voltage-gated sodium channel and the enzyme acetylcholinesterase (AChE) which confer resistance to pyrethroids and organophophate/carbamate insecticides respectively. This is leading to an increased fundamental understanding of how these insect nervous system proteins function and ideas for better/new pest management strategies.
IMB Jena Image Library of Biological Macromolecules: The IMB Jena Image Library of Biological Macromolecules contains visual and other information on three-dimensional biopolymer structures. It provides access to all structure entries deposited at the Protein Data Bank (PDB) or at the Nucleic Acid Database (NDB). In addition, general information on the architecture of biopolymer structures is available.
JalView - Java Alignment Editor: Jalview is a multiple alignment editor written in Java. It is used widely in a variety of web pages (e.g. the EBI Clustalw server and the Pfam protein domain database) but is available as a general purpose alignment editor.
Jpred: Jpred is an interactive protein secondary structure prediction Internet server. The server allows a single sequence or multiple alignment to be submitted, and returns predictions from six secondary structure prediction algorithms that exploit evolutionary information from multiple sequences.
Molecular Visualization Freeware (Rasmol) Email list: This email list is for discussion of RasMol, Chime, Protein Explorer, and other molecular visualization software (especially of the free variety)
MolMol: MOLecule analysis and MOLecule display: MOLMOL is a molecular graphics program for displaying, analyzing, and manipulating the three-dimensional structure of biological macromolecules, with special emphasis on the study of protein or DNA structures determined by NMR.
MPEx: Membrane Protein Explorer: for exploring the topology and other features of membrane proteins by means of hydropathy plots, using thermodynamic principles developed in our laboratory.
NDB Biological Structure Resource (BSR)(The): This site is a selection of databases, containing information about structure and other features of proteins and nuckleic acids. Good source of material.
One Gene - One Enzyme Theory: This led them to postulate the one gene - one enzyme theory: each gene in an organism controls the production of a specific enzyme. It is these enzymes that catalyze the reactions that lead to the phenotype of the organism. Today, we know that, in fact, not only enzymes, but all the other proteins from which the organism is built are encoded by genes.
PALI Phylogeny and ALIgnment of homologous protein structures: This database provides structure based sequence alignments for homologous proteins of known 3-D structure. The alignments available include those of pairwise (two proteins at a time) and multiple (simultaneous superposition of all the structures in a family). The database also provides dendrograms depicting phylogenetic relationships based on sequence and structural similarities.
Paper on JalView: Summary: Multiple sequence alignment remains a crucial method for understanding the function of groups of related nucleic acid and protein sequences. However, it is known that automatic multiple sequence alignments can often be improved by manual editing. Therefore, tools are needed to view and edit multiple sequence alignments. Due to growth in the sequence databases, multiple sequence alignments can often be large and difficult to view efficiently. The Jalview Java alignment editor is presented here, which enables fast viewing and editing of large multiple sequence alignments.
Pfam Homepage: Pfam is a high-quality comprehensive collection of protein domain families.
Plant Proteome Annotation Program: The Plant Proteome Annotation Program (PPAP) focuses on the annotation of plant-specific proteins and protein families.
Principles of Protein Structure Using the Internet: Birkbeck College\'s Advanced Certificate in the Principles of Protein Structure using the Internet is a tutor-assisted course accredited by the University of London. The course exploits modern developments in communications, which means that students from any country may study the course at home, at work or in your university. It is of one year duration and of final year undergraduate/postgraduate standard. The course coordinator is Dr Jim Pitts. Dr. Clare Sansom is the principal tutor and course material developer.
Prodom: The ProDom protein domain database consists of an automatic compilation of homologous domains detected in the SWISS-PROT database (Bairoch A, Boeckmann B, 1991, Nucleic Acids Res., 19:2247-2249) by the DOMAINER algorithm (Sonnhammer, E.L.L. & Kahn, D., 1994, Protein Sci. 3:482-492). It has been devised to assist with the analysis of the domain arrangement of proteins. Here is a outline of what this ProDom server can do for you
PROMALS: PROMALS constructs multiple protein sequence alignments using information from database searches and secondary structure prediction.
Prosite: PROSITE is a database of protein families and domains. It consists of biologically significant sites, patterns and profiles that help to reliably identify to which known protein family (if any) a new sequence belongs [More details / References / Disclaimer].
Protein Architecture tutorials: The Lehninger 3D Structure Tutorials are designed to accompany Principles of Biochemistry, 3rd edition, by Lehninger, Nelson, and Cox. They are built around the Chemscape Chime 2.0 plugin, which reads the atomic coordinates of a biological macromolecule and renders it as a fully interactive 3D structure.
Learn about all aspects of protein structure, from the chemical properties of the amino acids to the interaction of multiple chains in giant molecules.
Protein Data Bank Docs: The Protein Data Bank (PDB) is an archive of experimentally determined three-dimensional structures of biological macromolecules, serving a global community of researchers, educators, and students.
Protein Databases at EBI: The EBI has a developed and maintained a number of protein related databases.
Protein Explorer: Protein Explorer is free software for visualizing the three-dimensional structures of protein, DNA, and RNA macromolecules, and their interactions and binding of ligands, inhibitors, and drugs. It is arguably the easiest-to-use software of its kind.
Protein Information Resource: The Protein Information Resource (PIR), maintains the PIR-International Protein Sequence Database --- a comprehensive, annotated, and non-redundant set of protein sequence databases in which entries are classified into family groups and alignments of each group are available.
Protein sequence analysis at UCL: Our research concerns protein sequence analysis, primarily exploiting the technique of protein `fingerprinting\' (which uses conserved motifs to characterise particular folds and functionalities). We maintain a database of fingerprints (PRINTS), which complements PROSITE. We aim to improve fingerprint potency, to enhance predictive power in the Twilight Zone. We also design software to display sequence and structural data in visually-striking ways (e.g. using Java).
ProtParam: (References) is a tool which allows the computation of various physical and chemical parameters for a given protein stored in SWISS-PROT or for a user entered sequence. The computed parameters include the molecular weight, theoretical pI, amino acid composition, extinction coefficient, estimated half-life, instability index, aliphatic index and grand average of hydropathicity (GRAVY)
PSORT WWW Server: A WWW Server for Analyzing and Predicting Protein Sorting Signals Coded in Amino Acid Sequence
RASCAL: rapid scanning and correction of multiple sequence alignments : The accuracy and reliability of RASCAL is demonstrated using: (i) alignments from the BAliBASE benchmark database, where significant improvements were often observed, with no deterioration of the existing high-quality regions, (ii) a large scale study involving 946 alignments from the ProDom protein domain database, where alignment quality was increased in 68% of the cases; and (iii) an automatic pipeline to obtain a high-quality alignment of 695 full-length nuclear receptor proteins, which took 11 min on a DEC Alpha 6100 computer
Rasmol: V2.6 Molecular Visualisation Program . RasMol2 is a molecular graphics program intended for the visualisation of proteins, nucleic acids and small molecules. The program is aimed at display, teaching and generation of publication quality images. RasMol runs on Microsoft Windows, Apple Macintosh, UNIX and VMS systems.
SAT: Sequence Alignment Teacher: Dynamic programming (DP) is a general optimization strategy that is successfully used across various disciplines of science. In bioinformatics, it is widely applied in calculating the optimal alignment between pairs of protein or DNA sequences. These alignments form the basis of new, verifiable biological hypothesis. Despite its importance, there are no interactive tools available for training and education on understanding the DP algorithm. Here, we introduce an interactive computer application with a graphical interface, for the purpose of educating students about DP. The program displays the DP scoring matrix and the resulting optimal alignment(s), while allowing the user to modify key parameters such as the values in the similarity matrix, the sequence alignment algorithm version and the gap opening/extension penalties.
Scop: Structural Classification of Proteins: Welcome to scop: Structural Classification of Proteins. Release 1.35. 5493 PDB Entries (3 Mar 97). 10781 Domains. 138 Literature References.
SCORPION (amino acid frequences): SCORPION is the WWW tool for analysis of the amino acid frequences within protein chain(s) (of given pdb file or group of pdb files) as well as foranalysis of 3D contacts of C-alpha and/or Last Hevy Atoms in the residue side chain (LHA). Convinient Graphical presentation can be used for identification of specific interactions for given family of the proteins or given domains.
Sickle Cell Anemia, from the Department of Radiology and Nuclear Medicine, Bethesda, Maryland: Sickle Cell Anemia (SCA) is caused by a change in the chemical composition of the hemoglobin protein that carries oxygen inside of the red blood cells (RBC's).
SIGFIND - Signal Peptide Prediction Server (Human): This software (SIGFIND) predicts signal peptides at the start of protein sequences or searches open reading frames with a potential signal peptide coded in nucleotide sequences. The sig.pep. score along the sequence indicates the location and size of the signal-peptide. This score ranges from 0 (=no signal peptide) to 9 (=max. score for presence of a signal peptide). The range where this score drops from high to low indicates the approximate position of the cleavage site.
SIGMA: The entire Sigma catalog on line. Search by name, number, chemical structure and any key word. All Biochemicals for any type of laboratory work. All types of PCR reagents (Taq, JumpStart Taq, RedTaq, AccuTaq, dNTPs, custom oligos etc) Sequencing reagents (gels, plates, clean-up kits) DNA and RNA purification kits (plasmid, genomic, etc) Recombinant protein expression (Trasnfection reagents, vectors, media, competent cells, purification supports, western blotting reagents etc) Cell culture reagents (media, fetal bovine serum) Cell signaling reagents (antibodies, reagents, kits)

Package inserts on-line. MSDS info on-line. Orders taken on-line - handled by your local Sigma-Aldrich office. Pricing on-line in most national currencies. Technical Services ("Ask a Scientist") on-line
Spanish Omelette: analogy to fundamental dogma: The following is a good way to show the relationships among cell, nucleus, genes, chromosome, ribosome, replication, mitosis, transcription, translation, DNA, RNA, amino acids and proteins, genotype, phenotype, and genetic vs. environmental causes of cell defects.
Staden Site at sanger: The Staden Package consists of a series of tools for DNA sequence preparation (pregap4), assembly (gap4), editing (gap4) and DNA/protein sequence analysis (spin). The package was originally developed at the MRC-LMB in Cambridge. It is now open source (BSD licence) and is hosted on sourceforge.net.
Stratagene - Eagle Sight software:
Direct imaging of nucleic acid or protein gels stained with ethidium bromide,
Coomassie® Blue, SYBR® Green or silver stains
Digital imaging of fluorescent TLC plate-based assays, blots or ELISA plates
Digital imaging of autoradiographs
Imaging and analyzing chemiluminescent samples
Colony and plaque counting
Structural Biophysics Web Resources: A collection of links to Web Sites of value to protein scientists
Swiss PDB Viewer: Swiss-PdbViewer is an application that provides a user friendly interface allowing to analyse several proteins at the same time. The proteins can be superimposed in order to deduce structural alignments and compare their active sites or any other relevant parts. Amino acid mutations, H-bonds, angles and distances between atoms are easy to obtain thanks to the intuitive graphic and menu interface.
Moreover, Swiss-PdbViewer is tightly linked to Swiss-Model, an automated homology modelling server running at Glaxo Welcome Experimental Research in Geneva.
SWISS-MODEL: An Automated Comparative Protein Modelling Server: SWISS-MODEL is a fully automated protein structure homology-modeling server, accessible via the ExPASy web server, or from the program DeepView (Swiss Pdb-Viewer). The purpose of this server is to make Protein Modelling accessible to all biochemists and molecular biologists World Wide.
SWISS-PROT : Annotated Protein Database: SWISS-PROT is a curated protein sequence database which strives to provide a high level of annotations (such as the description of the function of a protein, its domains structure, post-translational modifications, variants, etc), a minimal level of redundancy and high level of integration with other databases (Disclaimer).
System Biology, the 21st century Science: Systems biology is the study of an organism, viewed as an integrated and interacting network of genes, proteins and biochemical reactions which give rise to life. Instead of analyzing individual components or aspects of the organism, such as sugar metabolism or a cell nucleus, systems biologists focus on all the components and the interactions among them, all as part of one system....
The Tumor Gene Database: The Tumor Gene Database contains information about genes which are targets for cancer-causing mutations; proto-oncogenes and tumor supressor genes. Its goal is to provide a standard set of facts (e.g. protein size, biochemical activity, chromosomal location, ...) about all known tumor genes. At present, the database contains over 2600 facts on over 300 genes.
TIGR - Genome Projects: TIGR\'s Genome Projects are a collection of curated databases containing DNA and protein sequence, gene expression, cellular role, protein family, and taxonomic data for microbes, plants and humans.
TOPSAN: The TOPSAN project was developed to collect, share, and distribute information about protein three-dimensional structures. TOPSAN will serve as a portal for the scientific community to learn about protein structures solved by SG centers, and also to contribute their expertise in annotating protein function.
Tree inference at the T-REX server: The most comprehensive web server version includes methods for Visualization and interactive manipulation of phylogenetic trees (using Hierarchical, Radial and Axial types of drawing); Inference of phylogenetic trees using distance (NJ, BioNJ, UNJ, ADDTREE, MW, FITCH, Circular order reconstruction),parsimony (DNAPARS, PROTPARS, PARS, DOLLOP) and maximum likelihood (PHYML, DNAML, DNAMLK, PROML, PROMLK) based approaches; Inference of phylogenetic trees form incomplete distance matrices; Inference of phylogenetic networks (i.e. Reticulograms); Detection of horizontal gene transfers; Multiple sequence alignment (ClustalW), Sequence to distance transformations(using Uncorrected, Jukes-Cantor, Tajima-Nei, Kimura 2-parameter, Tamura, Jin-Nei gamma, Kimura protein, LogDet and F84 distances); Computation of the Robison and Foulds topological distance between two or more trees. The program can also carry out bootstrap and jackknife resampling to assess strength of support of the tree and network branches.
Tutorial on ClustalW: Clustal W is a general purpose global multiple sequence alignment program for DNA or proteins. It produces biologically meaningful multiple sequence alignments of divergent sequences. It calculates the best match for the selected sequences, and lines them up so that the identities, similarities and differences can be seen. Evolutionary relationships can be seen via viewing Cladograms or Phylograms.
UGENE - Unipro: UGENE is a free cross-platform genome analysis suite. Multiple sequence alignment using MUSCLE 3,4 and KAlign; HMM profiles build and search, based on the source of HMMER 2 and HMMER 3; PCR Primers design using Primer 3; Protein secondary structure prediction using GOR IV and PSIPRED; Phylogenetic analysis with Phylip; Search for restriction enzymes and integration with REBASE; Extremely fast repeat finder; DNA reference assembly using Bowtie; Search for transcription factor binding sites using SITECON; Protein back translation; ORF finder; Complete Smith-Waterman algorithm implementation; Comparing genomes using dotplot view.
UniProt: The mission of UniProt is to provide the scientific community with a comprehensive, high-quality and freely accessible resource of protein sequence and functional information.
UniProtKB: The UniProt Knowledgebase (UniProtKB) is the central hub for the collection of functional information on proteins, with accurate, consistent and rich annotation. In addition to capturing the core data mandatory for each UniProtKB entry (mainly, the amino acid sequence, protein name or description, taxonomic data and citation information), as much annotation information as possible is added. This includes widely accepted biological ontologies, classifications and cross-references, and clear indications of the quality of annotation in the form of evidence attribution of experimental and computational data.
Viral Genetics: Viruses have a simple structure consisting usually of nucleic acid packed into a protein head. They lack the metabolic machinery for isolated mutiplication and must invade a host cell in order to reproduce. This parasitic lifestyle gives rise to some interesting reproductive cycles which we will explore in this chapter.
ViralZone: ViralZone is a portal to facilitate access to UniProtKB/Swiss-Prot viral protein entries. (virus)
WHATIF: WHAT IF is a versatile protein structure analysis program that can be used for mutant prediction, structure verification, molecular graphics, etc.

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