The Molecular Biology Notebook Online
A Beginners' Guide to Molecular Biology

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Nucleic Acids

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Group of biologically important molecules including DNA and RNA.

View Dr Chromo's lecture on 'RNA'

View Dr Chromo's lecture on ' DNA'

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Pronounce:

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Related Links

This is a search for nucleic in our database

• Atlas of Nucleic Acid Containing Structures: The goal of the Nucleic Acid Database Project (NDB) is to assemble and distribute structural information about nucleic acids.
• BCM Search Launcher :: The BCM Search Launcher organizes and simplifies molecular biology-related search and analysis services available on the WWW. It provides a single point-of-entry for related services, for example, a single page for launching nucleic acid sequence searches using standard parameters. See last newsletter
• Cis-Peptide Bonds in Proteins: The IMB Jena Image Library of Biological Macromolecules contains visual and other information on three-dimensional biopolymer structures. It provides access to all structure entries deposited at the Protein Data Bank (PDB) or at the Nucleic Acid Database (NDB).
• Deoxy-Ribonucleotides and Watson-Crick Basepairs: The IMB Jena Image Library of Biological Macromolecules contains visual and other information on three-dimensional biopolymer structures. It provides access to all structure entries deposited at the Protein Data Bank (PDB) or at the Nucleic Acid Database (NDB).
• GenBank: GenBank is the NIH genetic sequence database, an annotated collection of all publicly available DNA sequences ( Nucleic Acids Research 1998 Jan 1;26(1):1-7). There are approximately 1,622,000,000 bases in 2,356,000 sequence records as of June 1998. As an example, you may view the record for the neurofibromatosis gene.
• Gene Designer 2.0 : FREE bioinformatics software application. The dynamic drag-and-drop sequence functionality to create genes with Gene Designer has been awarded US Patent #7,805,252. This unique interface technology created by DNA2.0 scientists enables users to quickly represent nucleic acid sequences and to move them around with ease.
• IMB Jena Image Library of Biological Macromolecules: The IMB Jena Image Library of Biological Macromolecules contains visual and other information on three-dimensional biopolymer structures. It provides access to all structure entries deposited at the Protein Data Bank (PDB) or at the Nucleic Acid Database (NDB). In addition, general information on the architecture of biopolymer structures is available.
• Paper on JalView: Summary: Multiple sequence alignment remains a crucial method for understanding the function of groups of related nucleic acid and protein sequences. However, it is known that automatic multiple sequence alignments can often be improved by manual editing. Therefore, tools are needed to view and edit multiple sequence alignments. Due to growth in the sequence databases, multiple sequence alignments can often be large and difficult to view efficiently. The Jalview Java alignment editor is presented here, which enables fast viewing and editing of large multiple sequence alignments.
• Prodom: The ProDom protein domain database consists of an automatic compilation of homologous domains detected in the SWISS-PROT database (Bairoch A, Boeckmann B, 1991, Nucleic Acids Res., 19:2247-2249) by the DOMAINER algorithm (Sonnhammer, E.L.L. & Kahn, D., 1994, Protein Sci. 3:482-492). It has been devised to assist with the analysis of the domain arrangement of proteins. Here is a outline of what this ProDom server can do for you
• Rasmol: V2.6 Molecular Visualisation Program . RasMol2 is a molecular graphics program intended for the visualisation of proteins, nucleic acids and small molecules. The program is aimed at display, teaching and generation of publication quality images. RasMol runs on Microsoft Windows, Apple Macintosh, UNIX and VMS systems.
• Stratagene - Eagle Sight software:
  Direct imaging of nucleic acid or protein gels stained with ethidium bromide,
  Coomassie® Blue, SYBR® Green or silver stains
  Digital imaging of fluorescent TLC plate-based assays, blots or ELISA plates
  Digital imaging of autoradiographs
  Imaging and analyzing chemiluminescent samples
  Colony and plaque counting
• The 1989 Nobel Prize in Chemistry: This yearŽs Nobel Prize in chemistry has been awarded to Sidney Altman, USA and Thomas Cech, USA for their discovery that RNA (ribonucleic acid) in living cells is not only a molecule of heredity but also can function as a biocatalyst.
• The Discovery of the Molecular Structure of DNA - The Double Helix: The work of many scientists paved the way for the exploration of DNA. Way back in 1868, almost a century before the Nobel Prize was awarded to Watson, Crick and Wilkins, a young Swiss physician named Friedrich Miescher, isolated something no one had ever seen before from the nuclei of cells. He called the compound nuclein. This is today called nucleic acid, the NA in DNA (deoxyribo-nucleic-acid) and RNA (ribo-nucleic-acid).
• Viral Genetics: Viruses have a simple structure consisting usually of nucleic acid packed into a protein head. They lack the metabolic machinery for isolated mutiplication and must invade a host cell in order to reproduce. This parasitic lifestyle gives rise to some interesting reproductive cycles which we will explore in this chapter.

nucleic on Wikipedia

nucleic at Answers. com

New Links

-AIGO: Analysis and Intercomparison of Gene Ontology functional annotations
AIGO is a Python library for the Analysis and Inter-comparison of Gene Ontology (GO) functional anno...
-OmniMapFree
OmniMapFree is a computer program for displaying and analysing the genome of any organism. You can u...

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Web technical : Nathalie Castells-Brooke

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