The Molecular Biology Notebook Online
A Beginners' Guide to Molecular Biology

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Expression

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The process by which a gene's coded information is converted into the structures present and operating in the cell. Expressed genes include those that are transcribed into mRNA, and then translated into protein and those that are transcribed into RNA but not translated into protein, ie includes both introns and exons.

View Dr Chromo's lecture on 'Proteins'.

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Related Links

This is a search for expression in our database

• Anatomy of a Comparative Gene Expression Study: DNA microarrays are perfectly suited for comparing gene expression in different populations of cells. The hows and whys of such an experiment provide insight into the power of microarrays, their limitations, and the kinds of biological questions which they can help to answer...
• ArrayExpress Database: the European Bioinformatics Institute is committed to establishing a public repository for microarray based gene expression data, named ArrayExpress. Currently the EBI is establishing a pilot database containing microarray gene expression data that are available publicly.
• ChromDB: The Plant Chromatin Database: The mission of ChromDB is to bring together information on homologs of chromatin-associated proteins encoded by plant genomes, organize this information logically and in a comparative manner across species (with reference to other eukaryotes to the extent possible), and make it readily accessible to any members of the research and teaching communities who might be interested in the role played by chromatin proteins in the control of gene expression and genome organization. Our first priority is to provide (a) complete sets of genes encoding chromatin-associated proteins (CAPs) for those plant species with complete or near-complete genome sequences (currently Arabidopsis and rice, with poplar to be displayed in the future), (b) the best available splicing models and predicted protein sequences for these genes, and (c) a molecular phylogenetic context for understanding the evolutionary diversification of these protein families during plant evolution with reference to animal and fungal homologs. Our next priorities will be to identify and present CAP genes in all available EST and partial genomic sequences of other plant species, as well as to provide information regarding their biochemical, developmental, physiological, and cellular functions through a community annotation mechanism.
• Cytoscape: Cytoscape is an open source bioinformatics software platform for visualizing molecular interaction networks and integrating these interactions with gene expression profiles and other state data. Cytoscape is available as a platform-independent open-source Java application, released under the terms of the LGPL.
• Expression Profiler: Expression Profiler is a set of tools for the clustering, analysis and visualization of gene expression and sequence data.
• Gene Regulation - BioBase: Site with a lot of database for gene expression and gene regulation
• GeneSpring: cutting-edge tools for expression analysis: GeneSpring is widely regarded as the gold standard for expression data analysis. When you use GeneSpring, you join thousands of elite scientists worldwide who depend on its sophisticated analysis techniques to advance their research. Designed to meet the needs of the individual researcher, GeneSpring seamlessly interfaces with Silicon Genetics’ Signet software, which provides a highly scalable platform for enterprise- level genomic research
• Large-Scale Gene Expression and Microarray Links and Resources: This site is a collection of web resources and pointers to information on large-scale gene expression studies, and especially microarray technologies. The links included are biased towards the development and applications of informatics and bioinformatics for these technologies.
• Microarray Gene Expression Database Group: The MGED group is an open discussion group initially established at the Microarray Gene Expression Database meeting MGED 1 (November, 1999, Cambridge, UK). The goal of the group is to facilitate the adoption of standards for DNA-array experiment annotation and data representation, as well as the introduction of standard experimental controls and data normalisation methods.
• MicroArray related activities at the EBI: These pages are a jumping point to activities at the European Bioinformatics Institute that focus on microarrays, the gene expression data that results from them, the issues revolving around the immense influx of this data, and of course the analysis that one would like to perform on it.
• Principe des DNA sur Puce: Les puces à ADN permettent de mesurer et de visualiser très rapidement les différences d'expression entre les gènes et ceci à l'échelle d'un génome complet. Si la mise en oeuvre de la technique est assez compliquée, son principe est très simple. En voici les principales étapes
• REST-284: Relative Expression Software Tool: Therefore new software tools were established, named REST © (Relative Expression Software Tool), which compare two or more treatments groups or conditions (in REST-MCS), with up to 100 data points in sample or control group (in REST-XL), for multiple reference genes and up to 15 target genes (in REST-384) . The mathematical model used is based on the correction for exact PCR efficiencies and the mean crossing point deviation between sample group(s) and control group(s). Subsequently the expression ratio results of the investigated transcripts are tested for significance by a Pair Wise Fixed Reallocation Randomisation Test © and plotted using standard error (SE) estimation via a complex Taylor algorithm.
• SIGMA: The entire Sigma catalog on line. Search by name, number, chemical structure and any key word. All Biochemicals for any type of laboratory work. All types of PCR reagents (Taq, JumpStart Taq, RedTaq, AccuTaq, dNTPs, custom oligos etc) Sequencing reagents (gels, plates, clean-up kits) DNA and RNA purification kits (plasmid, genomic, etc) Recombinant protein expression (Trasnfection reagents, vectors, media, competent cells, purification supports, western blotting reagents etc) Cell culture reagents (media, fetal bovine serum) Cell signaling reagents (antibodies, reagents, kits)
  
  Package inserts on-line. MSDS info on-line. Orders taken on-line - handled by your local Sigma-Aldrich office. Pricing on-line in most national currencies. Technical Services ("Ask a Scientist") on-line
• TIGR - Genome Projects: TIGR\'s Genome Projects are a collection of curated databases containing DNA and protein sequence, gene expression, cellular role, protein family, and taxonomic data for microbes, plants and humans.

expression on Wikipedia

expression at Answers. com

New Links

-AIGO: Analysis and Intercomparison of Gene Ontology functional annotations
AIGO is a Python library for the Analysis and Inter-comparison of Gene Ontology (GO) functional anno...
-OmniMapFree
OmniMapFree is a computer program for displaying and analysing the genome of any organism. You can u...

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Web technical : Nathalie Castells-Brooke

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