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Lin Field

Biological Chemistry

Prof Linda M Field:
Publication List

Zhou, J-J., He, X.L., Pickett, J.A. and Field, L.M. (2008). Identification of odorant binding proteins of the yellow fever mosquito Aedes aegypti: Genome annotation and comparative analyses. Ins. Mol. Biol. 17, 147-163

Davies, T.G.E., O’Reilly, A.O., Field, L.M., Wallace, B.A. and Williamson, M.S. (2008). Knockdown resistance: from target site mutations to molecular modeling. Pest. Manag. Sci. (in press)

Khot, A.C., Bingham, G.V., Field, L.M. and Moores, G.D. (2008). A novel assay reveals blockade of esterases by piperonyl butoxide (PBO). Pest. Manag. Sci. (in press)

Bass, C.B., Williamson, M.S. and Field, L.M. (2008). Development of a multiplex real-time PCR assay for identification of members of the Anopheles gambiae species complex. Acta Tropica (in press)

Bingham, G, Gunning, R.V., Gorman, K., Field, L.M. and Moores, G.D. (2007). Temporal synergism by microencapsulation of piperonyl butoxide and α-cypermethrin overcomes insecticide resistance in crop pests. Pest. Man. Sci. 63, 276-281.

Davies, T.G.E., Usherwood, P.N.R., Field, L.M. and Williamson, M.S. (2007). A comparative study of voltage-gated sodium channels in the Insecta: implications for pyrethroid reistance in Anopheline and other Neopteran species. Insect Mol Biol. 16, 361-375.

Davies, T.G.E., Field, L.M., Usherwood, P.N.R. and Williamson, M.S. (2007). DDT, pyrethrins, pyrethroids and insect sodium channels. IUBMB, 59, 151-162.

Bass, C., Nikou, D., Donnelly, M.J.,Williamson M.S.,Ranson, H., Ball, A., Vontas J. and Field, L.M. (2007). Detection of knockdown resistance (kdr) mutations in Anopheles gambiae: a comparison of two new high-throughput assays with existing methods. Malaria J., 6,111-.

Usherwood, P.N.R., Mellor, I.R., Peng, F., Vais, H., Khambay, B.P.S., Davies, T.G.E., Field, L.M. and Williamson, M.W. (2007). Mutations in DIIS5 and the DIIS4-S4 linker of the Drosophila melanogaster para sodium channel characterise binding domains for pyrethroids and DDT. FEBS Letts 581, 5485-5492.

Bingham, G., Gunning, R.V., Delogu, G., Borzatta, V., Field, L.M. and Moores, G.D. (2007). Temporal Synergism can Enhance Carbamate and Neonicotinoid Insecticidal Activity against Resistant Crop Pests.Pest Manag. Sci. 64, 81-85.

Bass, C., Wilding C., Donnelly, M.J., Williamson, M.S. and Field, L.M. (2007). Identification of the main malaria vectors in the Anopheles gambiae species complex using a TaqMan real-time PCR assay. Malaria J. 6, 155-

Prosser, I.M., Adams, R.T., Beale, M.H., Hawkins, N.D., Pillips, A.L., Pickett, J.A. and Field, L.M. (2006). Cloning and functional characterisation of a cis-muuroladiene synthase from Black Peppermint (Mentha x piperita) and direct evidence for a chemotype unable to synthesise farnesenes. Phytochem. 67, 1564-1571.

Bass, C., Lansdell, S.J., Millar, N.S., Schroeder, I., Turberg, A., Field, L.M. and Williamson, M.S. (2006). Molecular characterisation of nicotinic acetylcholine receptor subunits from the cat flea, Ctenocephalides felis (Siphonaptera: Publicidae). Ins. Bioc. Mol. Biol. 36, 86-96.

O’Reilly, A.O., Khambay, B.P.S., Williamson, M.S., Field, L.M., Wallace, B.A. and Davies, T.G.E. (2006). Modelling insecticide binding sites at the voltage-gated sodium channel. Biochem. J. 396, 255-263.

Zhou, J-J, Kan, Y., Antoniw, J., Pickett, J.A. and Field, L.M. (2006). Genome and EST analyses and expression of a gene family with putative functions in insect chemoreception. Chemical Senses 31, 453-465.

Beale, M.H., Birkett, M.A., Bruce, T.J.A., Chamberlain, K., Field, L.M., Huttly, A.K., Martin, J.L., Parker, R., Phillips, A.L., Pickett, J.A., Prosser, I.M., Shewry, P.R., Smart, L.E., Wadhams, L.J., Woodcock, C.M. and Zhang, Y. (2006). Aphid alarm pheromone produced by transgenic plants affects aphid and parasitoid behaviour. Proc. Natl. Acad Sci. USA 103, 10509-10513.

Gunning, R.V., Nicholson, I.C., Kemp, F.C., Borzatta, V., Cottade, E.L.A., Field, L.M. and Moores, G.D. (2006). Piperonyl butoxide, restores the efficacy of Bacillus thuringiensis toxin in transgenic cotton against resistant Helicoverpa armigera. Biopesticides Intl. 2, 129-136.

Li, Z-X., Pickett, J.A., Field, L.M. and Zhou, J-J. (2005). Identification and expression of odorant-binding proteins of the malaria-carrying mosquitoes Anopheles gambiae and Anopheles arabiensis. Arch. Insect Biochem. Physiol. 58, 175-189

Jacobs, S.P., Liggins, A.P., Zhou, J-J, Pickett, J.A., Pelosi, P. and Field, L.M. (2005). OS-D-like genes and their expression in aphids (Hemiptera:Aphididae). Ins. Mol. Biol. 14, 423-432.

Zhou, J.-J., Huang, W., Zhang, G.-A., Pickett, J.A. and Field, L.M. (2004). “Plus-C” odorant-binding protein genes in two Drosophila species and the malaria mosquito Anopheles gambiaeGene 327, 117-129.


Zhou, J.-J., Zhang, G.-A., Huang, W., Birkett, M.A., Field, L.M., Pickett, J.A. and Pelosi, P. (2004). Revisiting odorant-binding protein lush of Drosophila melanogaster: Evidence for odour recognition and discrimination. FEBS Letters 558, 23-26.

Field, L.M., Lyko, F., Mandrioli, M. and Prantera, G. (2004). DNA methylation in insects. Ins.  Mol. Biol. 13, 109-115.

Williamson, M.S., Andrews, M.C., Anstead, J.A., Field, L.M., Moores, G.D., Foster, S.J., Devonshire, A.L. and Denholm, I. (2004). A mechanism-based approach to monitoring for insecticide resistance in the peach-potato aphid, Myzus persicae. In: Neurotox ’03: Neurotoxicological Targets from Functional Genomics and Proteomics. SCI. Eds Beadle, D.J., Mellor, I.R. and Usherwood P.N.R. pp87-95.

Bass, C., Schroeder, I., Turberg, A., Field, L.M. and Williamson, M.S. (2004). Identification of the Rdl mutation in laboratory and field strains of the cat flea, Ctenocephalides felis (Siphonaptera: Pulicidae).  Pest Manag. Sci. 60, 1157-1162.

Andrews, M.C., Callaghan, A., Field, L.M., Williamson, M.S. and Moores, G.D. (2004). Identification of mutations conferring insecticide-insensitive AChE in the cotton-Melon aphid, Aphis gossypii Glover. Ins. Mol. Biol. 13, 555-561.

Bass, C., Schroeder, I., Turberg, A., Field, L.M. and Williamson, M.S. (2004). Identification of mutations associated with pyrethroid resistance in the para-type sodium channel of the cat flea, Ctenocephalides felis. Ins. Bioc. Mol. Biol. 34, 1305-1313.

Andrews, M.C., Callaghan, A., Williamson, M.S., Field, L.M. and Moores, G.D. (2004). A single amino acid substitution founding pirimicarb-insensitive acetlycholinesterase (AChE) of the peach-potato aphid, Myzus persicae (Sulz.). In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects. Eds Inestrosa, N.C. and Campos, E.O. pp 229-231.

Moss, S.R., Cocker, K.M., Brown, A.C., Hall, L. and Field, L.M. (2003). Characterisation of target-site resistance to ACCase-inhibiting herbicides in the weed Alopecurus myosuroides (black-grass).  Pest Manag. Sci. 59, 190-201.

Field, L.M., Jacobs, S.P., Zhou, J-J. and Pickett, J.A. (2003). Odorant binding proteins and chemosensory proteins in Drosophila and aphids.  Comparative Biochemistry and Physiology Part A, S65.

Field, L.M. and Blackman, R.L. (2003). Insecticide resistance in the aphid Myzus persicae (Sulzer): chromosome location and epigenetic effects on esterase gene expression in clonal lineages.  Biological J. Linnean Society 79, 107-113.

Field, L. (2003). The use of insects as biosensors for the detection of volatile compounds. European Biophysics Journal 32, 180.

Javed, N., Viner, R., Williamson, M.S., Field, L.M. and Moores, G.D. (2003). Characterisation of acetylcholinesterases, and their genes from the hemipteran species Myzus persicae (Sulzer), Aphis gosypii (Glover), Bemisia tabaci (Gennadius) and Trialeurodes vaporariorum (Westwood).  Ins. Mol.  Biol. 12, 613-620.

Field, L.M., Liggins, A.P., Jacobs, S.P., Zhou, J-J. and Pickett, J.A. (2002). Odorant binding proteins and chemosensory proteins in insects. Comparative Biochem. & Physiol. 132, S63/4.

Brown, A. C., Moss, S.R., Wilson Z.A. and Field, L.M. (2002). An isoleucine to leucine substitution in the ACCase of Alopecurus myosuroides (black grass) is associated with resistance to the herbicide sethoxydim.  Pestic. Biochem. Physiol. 72, 160-168.

Field, L.M. and Foster, S.P. (2002). Amplified esterase genes and their relationship with other insecticide resistance mechanisms in English field populations of the aphid, Myzus persicae (Sulzer).  Pest Manag. Sci. 58, 889-894.

Hemingway, J., Field, L., and Vontas, J. (2002). An overview of insecticide resistance. Science 298, 96-97.


Field, L.M., Blackman, R.L. and Devonshire, A.L. (2001). Evolution of amplified esterase genes as a mode of insecticide resistance in aphids. In: Biochemical Sites Important in Insecticide Action and Resistance. Ed. I. Ishaaya, Springer, Berlin, Heidelberg, New York, pp. 209-219.

Field, L.M. (2000). Methylation and expression of amplified esterase genes in the aphid Myzus persicaeBiochem. J. 349, 863-868.

Field, L.M., Pickett, J.A. and Wadhams, L.J. (2000). Molecular studies in insect olfaction. Ins. Mol. Biol. 9, 545-551.

Martinez-Torres, D., Foster, S.P., Field, L.M., Devonshire, A.L. and Williamson, M.S. (1999). A sodium channel point mutation is associated with resistance to DDT and pyrethroid insecticides in the peach-potato aphid, Myzus persicae (Sulzer) (Hemiptera : Aphididae).  Ins. Mol. Biol. 8, 339-346.

Blackman, R.L., Spence, J.M., Field, L.M., and Devonshire, A.L. (1999). Variation in the chromosomal distribution of amplified esterase (FE4) genes in Greek field populations of Myzus persicae (Sulzer).  Heredity 82, 80-86.

Field, L.M., Blackman, R.L., Tyler-Smith, C. and Devonshire, A.L. (1999). Relationship between amount of esterase and gene copy number in insecticide-resistant Myzus persicae (Sulzer).  Biochem. J. 339, 737-742.

Ono, M., Swanson, J.J., Field, L.M., Devonshire, A.L. and Siegfried, B.D. (1999). Amplification and methylation of an esterase gene associated with insecticide resistance in greenbugs, Schizaphis graminumIns. Bioc. Mol. Biol. 29, 1065-1073.

Field, L.M. and Devonshire, A.L. (1998). Evidence that the E4 and FE4 genes responsible for insecticide resistance in the aphid Myzus persicae are part of a gene family. Biochem. J. 330, 169-173.

Miflin, B.J. Field, L.M., Williamson, M.S., Devonshire, A.L. and Denholm, I. (1998). The use of gene sequences in combating pesticide resistance. In: Genomics, Commercial Opportunities from a Scientific Revolution.  Eds. Dixon, G.K., Copping, L.G. and Livingstone, D., SCI Bios. pp. 189-198.

Devonshire, A.L., Field, L.M., Foster, S.P., Moores, G.D., Williamson, M.S. and Blackman, R.L. (1998). The evolution of insecticide resistance in the peach-potato aphid, Myzus persicae.  Philos. Trans. Royal Soc. Series B 353, 1677-1684.

Field, L.M. and Devonshire, A.L. (1997). Structure and organisation of amplicons containing the E4 esterase genes responsible for insecticide resistance in the aphid Myzus persicae (Sulzer). Biochem. J.  322, 867-871.

Field, L.M., Anderson, A.P., Denholm, I., Foster, S.P., Harling, Z.K., Javed, N., Martinez-Torres, D., Moores, G.D., Williamson, M.S. and Devonshire, A.L. (1997). Use of biochemical and DNA diagnostics for characterising multiple mechanisms of insecticide resistance in the peach-potato aphid Myzus persicae (Sulzer). Pestic. Sci. 51, 283-289.

Hick, C.A., Field, L.M. and Devonshire, A.L. (1996). Changes in the methylation of amplified esterase DNA during loss and reselection of insecticide resistance in the peach-potato aphids, Myzus persicaeInsect Bioc. Mol. Biol. 26, 41-47.

Field, L.M., Devonshire, A.L. and Tyler-Smith, C. (1996). Analysis of amplicons containing the esterase genes responsible for insecticide resistance in the peach-potato aphid Myzus persicae (Sulzer).  Biochem. J. 313, 543-547.

Field, L.M., Hick, C.A., Devonshire, A.L., Javed, N., Spence, J.M. and Blackman, R.L. (1996). Expression of amplified esterase genes in insecticide-resistant Myzus persicae (Sulzer). In: Molecular Genetics and Ecology of Pesticide Resistance.  ACS Symposia Series. Ed. Brown, T.M. pp 72-79.

Blackman, R.L., Spence, J.M., Field, L.M., Javed, N., Devine, G.J. & Devonshire, A.L. (1996). Inheritance of the amplified esterase genes responsible for insecticide resistance in Myzus persicae (Homoptera: Aphididae). Heredity. 77, 154-167.

Field, L.M., Crick, S.E. and Devonshire, A.L. (1996). Polymerase chain reaction-based identification of insecticide resistance genes and DNA methylation in the aphid Myzus persicae (Sulzer).  Ins. Mol. Biol. 5, 197-202.

Blackman, R.L., Spence, J.M., Field, L.M. and Devonshire, A.L. (1995). Chromosomal location of the amplified esterase genes conferring resistance to insecticides in Myzus persicae (Homoptera: Aphididae).  Heredity 75, 297-302.

Field, L.M., Javed, N., Stribley, M.F. and Devonshire, A.L. (1994). The peach-potato aphid Myzus persicae and the tobacco aphid Myzus nicotianae have the same esterase-based mechanism of insecticide resistance. Ins. Mol. Biol. 3, 143-148.

Field, L.M., Williamson, M.S., Moores, G.D. and Devonshire, A.L. (1993). Cloning and analysis of the esterase genes, conferring insecticide resistance in the peach-potato aphid Myzus persicae.  Biochem. J. 294, 569-574.

Field, L.M. and Devonshire, A.L. (1992). Insecticide resistance by gene amplification in Myzus persicaeIn: Proc of SCI Int. Symp "Resistance '91" July 91 Monograph. Eds I. Denholm, A.L. Devonshire and D.W. Hollomon pp. 240-250.

Devonshire, A.L., Field, L.M. and Williamson, M.S. (1992). Molecular biology of insecticide resistance. In: Proc of RESL 16th Symp. "Insect Molecular Science" Eds. J.M. Crampton and P. Eggleston pp. 173-183.

Field, L.M. and Devonshire, A.L. (1992). Esterase genes conferring insecticide resistance in aphids.  In: Proc. Am. Chem. Soc. New York 1991. Eds. C.A. Mullin and J.G. Scott. pp. 209-217.

Devonshire, A.L. and Field L.M. (1991). Gene amplification and insecticide resistance.  Ann. Rev. Ent. 36, 1-23.

Field, L.M., Devonshire, A.L., ffrench-Constant, R.H. and Forde, B.G. (1989). The combined use of immunoassay and a DNA diagnostic technique to identify insecticide-resistant genotypes in the peach-potato aphid, Myzus persicae (Sulz.).  Pestic. Biochem. Physiol. 34, 174-178.

Field, L.M., Devonshire, A.L., ffrench-Constant, R.H. and Forde, B.G. (1989). The combined use of immunoassay and a DNA diagnostic technique to identify insecticide-resistant genotypes in the peach-potato aphid, Myzus persicae (Sulz.).  Pestic. Biochem. Physiol. 34, 174-178.

Field, L.M., Devonshire, A.L., ffrench-Constant, R.H. and Forde, B.G. (1989). Changes in DNA methylation are associated with loss of insecticide resistance in the peach-potato aphid Myzus persicae (Sulz.). FEBS letters, 243, 323-327.

Field, L.M., Devonshire, A.L. and Forde, B.G. (1988). Molecular evidence that insecticide resistance in peach-potato aphids (Myzus persicae Sulz.) results from amplification of an esterase gene. Biochem. J. 251, 309-312.