People › Miss Angela Doherty
Member› Maximising yield potential of wheat
MemberBiotechnology resources for arable crop transformation (BRACT)
The BRACT research programme aims to provide an efficient transformation capability for the main UK crops, while facilitating further improvements in transformation technology and delivery to the UK research community. It is a collaboration between Rothamsted Research and the John Innes Centre. The work at Rothamsted Research will focus on developing protocols for Agrobacterium-mediated wheat transformation, testing constructs in wheat and on developing ‘clean gene’ transformation methods for wheat.
To develop nutritionally enhanced wheat using a combination of improved varieties and innovative processing, with a focus on dietary fibre, resistant starch and phytochemicals. Should have a range of health benefits for consumers including reduced obesity and type 2 diabetes and improved bowel function. May also result in lower cardiovascular disease and reduced incidents of some forms of cancer.
The main objective of this project is to develop and improve GM technology in wheat by exploiting matrix attachment regions (MAR) sequences from the cereals maize and rice. The MARs will be used to stabilize transgene expression using a high molecular weight (HMW) glutenin subunit transgene as a marker. A novel approach will be taken in which the Ac/Ds transposable element system is used to generate new insertion sites after the primary transformation process, to ensure that lines with equal insertion numbers can be compared for MAR function and that the transgene loci examined are not biased by subjection to selection pressure.
Operates two national networks for monitoring insect populations in the UK. More...
Provides the research community access to a range of in situ state-of-the-art instrumentation in hydrologically isolated fields and farms to better address key issues in sustainable agriculture. More...
A database of interactions between pathogens and their hosts maintained at Rothamsted Research with international input. More...
These have been running since the mid 19th Century, provide a unique experimental system and archive of soil and plant samples. More...
Rothamsted Research receives
strategic funding from the BBSRC
|Contact UsDisclaimerFeedbackCareersCorporate InformationPress OfficeHow to find us||© Rothamsted Research 2013|